ArticleImaging neuroscience (Cambridge, Mass.)2026
Spatial covariance of mGluR5 density and structural degeneration in behavioral variant frontotemporal degeneration.
Melanie A Matyi, Maggie K Pecsok, Christopher A Olm, Hamsanandini Radhakrishnan, Laynie Dratch, Vivianna M Van Deerlin, Emma Rhodes, Jeffrey S Phillips, Philip A Cook, James C Gee and 4 more
Abstract read
In one paragraphArticle in Imaging neuroscience (Cambridge, Mass.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Maggie K PecsokBrain Behavior Lab, Neurodevelopmental and Psychosis Section, Department of Psychiatry, School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0001-6806-5423 Hamsanandini RadhakrishnanPenn Frontotemporal Degeneration Center, Department of Neurology, School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0002-4448-986X David RoalfBrain Behavior Lab, Neurodevelopmental and Psychosis Section, Department of Psychiatry, School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.ORCID https://orcid.org/0000-0002-1728-9782 Lauren MassimoPenn Frontotemporal Degeneration Center, Department of Neurology, School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Funding
Research Education ComponentP30AG072979 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DAVID A WOLK · 2021 to 2026
$24.8MUnderstanding Environmental Contributions to Heterogeneity in bvFTD.P01AG066597 · NIA · UNIVERSITY OF PENNSYLVANIA · PI David John Irwin, Corey T McMillan · 2020 to 2026
$18.8MSpreading Tau Pathology in Non-Amnestic Alzheimer's DiseaseR01AG054519 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jeffrey S Phillips · 2018 to 2026
$7.4MMultidimensional Approaches to Understanding Consequences and Mechanisms of Apathy in Frontotemporal DegenerationR01AG076832 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Lauren M Massimo · 2022 to 2026
$2.6MGlial-mediated Inflammation and Iron Accumulation in Frontotemporal DementiaR01AG090414 · NIA · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, David John Irwin · 2025 to 2026
$1.6MCross-disciplinary training in translational neuroimaging of ADRDT32AG076411 · NIA · UNIVERSITY OF PENNSYLVANIA · PI JOHN A DETRE, MURRAY GROSSMAN · 2022 to 2026
$1.5MNIA NIH HHS P01 AG066597NIA NIH HHS P30 AG072979NIA NIH HHS R01 AG054519NIA NIH HHS R01 AG076832NIA NIH HHS R01 AG090414NIA NIH HHS T32 AG076411
6 · The paper itselfAbstract
Post-mortem human brain tissue and
Indexed as
BrainFrontotemporal Lobar DegenerationReceptor, Metabotropic Glutamate 5AdultAgedFemaleHumansMaleMiddle AgedPositron-Emission TomographyGRM5 protein, humanReceptor, Metabotropic Glutamate 5behavioral variant frontotemporal degenerationexecutive functionglutamatespatial covariance
Identifiers
PMID42729732
PMCPMC13563532
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