ArticleACS omega2026
Fast Microwave-Assisted Ullmann-Type Coupling for the Synthesis of Multisubstituted Diaryl Ethers.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
12 authors.
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Abstract
A mild and rapid microwave-assisted Ullmann-type C-O coupling protocol catalyzed by copper-(II) complexes was developed and optimized for the efficient synthesis of a wide variety of diaryl ethers. The synthetic methodology is general and tolerant toward both electron-rich and electron-poor phenols and aryl halides. Furthermore, this protocol provides a practical and rapid methodology for preparing diaryl ethers with potential biological and pharmacological relevance and represents a rapid and operationally efficient alternative to conventional thermal methods, thereby widening the use of copper catalysis in organic synthesis.
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