ArticleUpsala journal of medical sciences2026
Multiple endocrine neoplasia type 1 with concurrent Cushing's disease, prolactinoma, and multifocal pancreatic neuroendocrine tumors including insulinoma: a case report.
Article in Upsala journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Multiple Endocrine Neoplasia type 1 Case presentation: A 28-year-old man presented with adrenocorticotropic hormone-dependent hypercortisolism and progressive cushingoid features. Pituitary Magnetic Resonance Imaging revealed a microadenoma, confirmed as a PitNET on histopathology. Concurrent PHPT and genetically confirmed MEN1 (splice-site pathogenic variant c.825-1G>A) were identified. Transsphenoidal surgery failed to achieve remission, and metyrapone provided partial control. Subtotal parathyroidectomy resulted in persistent PHPT. Imaging revealed multifocal pancreatic NETs with biochemically confirmed insulinoma. Lanreotide achieved complete resolution of hypoglycemia, while Conclusion: This case highlights the complexity of MEN1 with multiple functioning tumors and the clinical impact of hormonal interactions. It underscores the importance of multidisciplinary, individualized management, particularly when tumor multifocality limits surgical options. It also emphasizes the need to recognize complex endocrine syndromes in general clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.