ArticleFrontiers in pediatrics2026
Prediction of risk factors for respiratory failure in children with mycoplasma pneumoniae pneumonia based on clinical pulmonary infection scores.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Mycoplasma pneumoniae pneumonia (MPP) remains a leading cause of community-acquired pneumonia in children, with respiratory failure occurring in 15%-20% of hospitalized cases. Despite advances in understanding MPP pathogenesis, validated tools for early prediction of respiratory failure are lacking. This study aimed to develop and validate a nomogram based on Clinical Pulmonary Infection Score (CPIS) for individualized risk stratification in pediatric MPP. Methods: We conducted a retrospective cohort study of 305 children with confirmed MPP admitted to our hospital between July 2020 and December 2024. Patients were categorized into respiratory failure ( Results: Respiratory failure was associated with significantly higher rates of tachypnea (91.9% vs. 16.5%), interstitial changes (87.1% vs. 25.5%), and pleural effusion (74.2% vs. 24.7%) (all Conclusions: This CPIS-based nomogram provides a highly accurate, clinically practical tool for predicting respiratory failure in pediatric MPP. By integrating radiographic, inflammatory, and physiological parameters, it enables early identification of high-risk patients for enhanced monitoring and preemptive respiratory support, potentially improving outcomes in severe MPP.
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