Evidence map›Paper›PMID 42729389›Full record

ArticleFrontiers in pharmacology2026

Catechins as antibiofilm agents: molecular insights for virtual screening and in

Adnan Amin, Ahmad Khan, Haider Ali, Wajid Zaman, Sadia Chaman, Ali Zaman, Muhammad Kashif Majeed, Niamat Ullah, Muhammad Imran Aziz

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adnan AminDepartment of Life Sciences, Yeungnam University, Gyeongsan, Republic of Korea.
Ahmad KhanFaculty of Pharmacy, Dera IsmailKhan, Khyber Pakhtunkhwa, Pakistan.
Haider AliFaculty of Pharmacy, Dera IsmailKhan, Khyber Pakhtunkhwa, Pakistan.
Wajid ZamanDepartment of Life Sciences, Yeungnam University, Gyeongsan, Republic of Korea.
Sadia ChamanInstitute of Pharmaceutical Sciences, UVAS, Lahore, Pakistan.
Ali ZamanInstitute of Microbiology, FVAS, Gomal University, Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan.
Muhammad Kashif MajeedDepartment of Chemistry, School of Natural Sciences, National University of Sciences and Technology, Islamabad (NUST), Pakistan.
Niamat UllahFaculty of Pharmacy, Dera IsmailKhan, Khyber Pakhtunkhwa, Pakistan.
Muhammad Imran AzizFaculty of Pharmacy, Dera IsmailKhan, Khyber Pakhtunkhwa, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Bacterial Biofilms are of great concern because they are the main drivers of antimicrobial resistance. We investigated the potential of catechins against bacterial biofilms using advanced computational and Methods: The HPLC profiling of Results: Molecular docking on 2UV0 indicated a moderate interaction with targets, which was further confirmed by DFT analysis (Homo-Lumo). Root mean square fluctuations and normal mode analysis (NMA) further supported the chemical reactivity and possible protein-ligand stabilization profile of epicatechin gallate. Antimicrobial assay showed the highest inhibition by epigallocatechin against Conclusion: It was thus concluded that catechin possesses significant antibacterial and antibiofilm potential that be phenotypic response.

Indexed as

biofilmcatechinsDFTmolecular mechanismsquorum sensing

Identifiers

PMID42729389
PMCPMC13561943

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.