Evidence map›Paper›PMID 42729250›Full record

ArticleFrontiers in child and adolescent psychiatry2026

Co-designing and piloting adolescent-adapted social rhythm therapy for young people with unipolar and bipolar depression: a mixed-methods feasibility case series.

Gonzalo Salazar de Pablo, Claudia Aymerich, Zahra Kamran, Cecilia Sanjuan-Ortiz, Nuria Laherran-Cantera, Shantal Zeb, Eleonora Armyra, Allan H Young, Aditya Sharma, Cornelius Ani and 2 more

Abstract read
In one paragraph

Article in Frontiers in child and adolescent psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Gonzalo Salazar de PabloDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Claudia AymerichDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Zahra KamranDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Cecilia Sanjuan-OrtizDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Nuria Laherran-CanteraDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Shantal ZebDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Eleonora ArmyraDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Allan H YoungCentre for Affective Disorders (CfAD), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.
Aditya SharmaAcademic Psychiatry, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Cornelius AniDivision of Psychiatry, Imperial College London, London, United Kingdom.
Manasi KumarInstitute for Excellence in Health Equity, Department of Population Health, New York University Grossman School of Medicine, New York, NY, United States.
Holly A SwartzDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Depressive and bipolar disorders commonly emerge during adolescence and are associated with disturbances in sleep, daily routines and social rhythms, as well as functional impairment. Social Rhythm Therapy (SRT) targets these processes. However, adult-derived rhythm protocols do not adequately reflect adolescents' school and family schedules, developmental autonomy, social and digital routines, or preferences regarding monitoring. Direct youth co-design is therefore needed to improve developmental fit, engagement and feasibility. We addressed this gap by co-designing the Social Therapy for Adolescent Rhythms in Depression (STAR-D), an adolescent-adapted SRT intervention, and evaluating its feasibility and acceptability within routine Child and Adolescent Mental Health Services (CAMHS). Methods: A two-phase mixed-methods feasibility design was used. Phase 1 involved co-production and intervention adaptation using questionnaire feedback from 10 adolescents, an in-depth interview with one Young People's Advisory Group representative, and feedback from six clinicians. TIDieR principles guided intervention description and adaptation. Phase 2 piloted STAR-D in adolescents receiving care in Lambeth CAMHS, London, UK. Feasibility was assessed through referral, uptake, retention and completion. Acceptability was assessed through qualitative feedback. Exploratory clinical outcomes were described using measures of functioning, depressive symptoms and manic symptoms. Results: Phase 1 feedback identified priorities for intervention adaptation, including accessible language, explicit links between routines and mood, personalised goals and flexible delivery. These findings informed an eight-session STAR-D protocol. In Phase 2, seven young people were referred, six accepted and started STAR-D, and five completed all eight sessions. Participants described the intervention as supportive, collaborative and accessible. However, they suggested simplifying daily monitoring to reduce burden. Quantitative completion and missingness data for monitoring forms were not prospectively collected. Exploratory clinical trajectories were variable. Conclusion: STAR-D was feasible to deliver and acceptable to most participants in this small, uncontrolled, single-service pilot. The findings support further optimisation, particularly of routine monitoring, followed by a larger multicentre controlled mechanistic trial. Future work should test whether changes in sleep-wake regularity, daily routines and social rhythm stability mediate changes in mood and functioning, and should evaluate unipolar and bipolar presentations with sufficient diagnostic stratification.

Indexed as

adolescentsbipolar disorderco-designingdepressionsocial rhythm

Identifiers

PMID42729250
PMCPMC13562024

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.