SynthesisFrontiers in neurology2026
Predictors of seizures after endovascular aneurysm exclusion: an updated systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Endovascular aneurysm exclusion has revolutionized neurovascular care, yet postoperative seizures remain a significant cause of morbidity. As endovascular technologies evolve from simple coiling to complex flow diversion, identifying factors associated with postoperative seizures is essential for improving risk stratification and neurocritical care. This systematic review and meta-analysis, registered in PROSPERO (CRD420261375370), followed PRISMA 2020 guidelines. A comprehensive search of MEDLINE, Scopus, Embase, and the Cochrane Library was conducted through April 13, 2026. Studies published since 2016 investigating factors associated with seizures after endovascular treatment (coiling, flow diversion, or stent-assisted techniques) were included. Random-effects meta-analysis was performed using R to calculate pooled odds ratios (OR) and 95% confidence intervals (CI), with subgroup and sensitivity analyses performed where feasible. Six studies met the inclusion criteria for qualitative and quantitative synthesis. Radiological markers showed the strongest associations with post-procedural seizures. Hydrocephalus demonstrated the highest association (OR 3.91, 95% CI: 1.22 to 12.53), followed by Fisher grade 3 + 4 blood distribution (OR 3.29, 95% CI: 1.55 to 6.97, Systematic review registration: https://www.crd.york.ac.uk/prospero/search, identifier CRD420261375370.
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