Evidence map›Paper›PMID 42729163›Full record

ArticleFrontiers in medicine2026

Real-time vascular monitoring of PDLs and IPL for vascular treatment: effects of fluence and pulse duration on a rabbit ear model.

Tun Tun Aung, Yusang Hu, Xiaohan Liu, Manmei Long, Wanyi Wang, Khin Maung Htwe, Soe Lei May, Yuhao Sun, Yixin Zhang, Zheng Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tun Tun Aung *Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yusang Hu *Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Xiaohan Liu *Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Manmei LongDepartment of Pathology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Wanyi WangDepartment of Laser and Aesthetic Medicine, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
Khin Maung HtweSchool of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Soe Lei MayCollege of Stomatology, Shanghai Jiao Tong University, Shanghai, China.
Yuhao SunDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yixin ZhangDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zheng ZhangDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulsed dye lasers (PDLs) and intense pulsed light (IPL) are commonly used for treating cutaneous vascular diseases but lack standardized and reproducible treatment protocols. Reliable vascular models are needed to visually assess posttreatment responses. Methods: Sixteen male rabbits were divided into two groups, with each ear subdivided into three treatment regions. PDL treatment was applied with pulse durations of 0.45 ms (fluences: 4, 5.5, and 8 J/cm Results: The dorsal ear vessels of rabbits consisted of longitudinally arranged main blood vessels (MBVs) and fan-shaped branch blood vessels (BBVs), with diameters ranging from 150-300 μm and 90-120 μm, respectively. In the PDL treatment, effective vessel closure with limited peripheral tissue damage was achieved using 0.45 ms at 5.5 J/cm Conclusion: The rabbit ear vascular model, combined with dermoscopy, LSCI, and histopathology, provides a reproducible multimodal platform for longitudinal evaluation and systematic parameter screening, offering a reliable preclinical foundation for comparative assessment and protocol refinement prior to clinical translation.

Indexed as

animal modeldermoscopyintense pulsed lightlaser speckle contrast imaginglaser treatmentpulsed dye laserrabbitvascular monitoring

Identifiers

PMID42729163
PMCPMC13561808

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.