ArticleF1000Research2026
Effect of Combined CO₂ Laser Irradiation and Sodium Fluoride Varnish on Enamel Surface Morphology and Surface Elemental Composition: An In Vitro Split-Tooth Study.
Article in F1000Research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Fluoride administration plays a critical role in the management and prophylaxis of dental caries. Research indicates that laser irradiation can enhance the uptake of fluoride into dental enamel, an effect that is particularly pronounced when used as an adjunct to topical fluoride treatments. The present study aimed to evaluate the impact of CO Methods: Six human upper premolars, extracted for orthodontic reasons, were selected for this study. The roots were separated from the crowns, and each crown was then sectioned mesiodistally to create mesial and distal halves. These halves were assigned to either an experimental or a control group (n = 6 per group). All specimens received an application of 5% sodium fluoride (NaF) varnish. Subsequently, the samples in the experimental group were subjected to irradiation with a 1 W CO Results: Scanning electron microscopy (SEM) structural analysis revealed that the enamel surfaces in the fluoride alone group maintained a typical etched pattern with visible micropores. In contrast, the experimental group subjected to both sodium fluoride varnish and CO Conclusion: The combination of CO
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