ArticleF1000Research2025
Exploring infectious aneurysms through a series of cases in a tertiary care unit in South India.
Article in F1000Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and aims: Infectious aneurysm is an aneurysm of the arteries originating from endogenous bacteraemia due to bacterial or fungal origin. The major vessels involved are femoral, aorta, then intracranial visceral arteries and pulmonary arteries. These aneurysms are identified by their fusiform shape, multiple, distal location involving the entire wall of the vessel and changing morphology on repeat imaging studies. The study aims to discuss the clinical presentation & management of post infectious aneurysms. Methods: This is a retrospective study of 11 case series of postinfectious aneurysms over a period of 10 years admitted at a tertiary care hospital. The detailed clinical data that included the clinical presentation, diagnostic and treatment was studied from the hospital medical records department and laboratory information system. Results: Among the 11 patients diagnosed with aneurysms, 4 presented with intracranial, 4 with intra pulmonary and 3 with intra-abdominal aortic aneurysms involvement. Source was either of bacterial cause such as Conclusion: High index of suspicion in patients presenting with fever, elevated C-reactive protein, ESR, total counts with sudden development of atypical aneurysms requires timely blood culture pre and post procedure. Definitive surgical/endovascular under antibiotic coverage at the earliest is a prerequisite in the management to prevent re-rupture.
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