ArticleBMC medical imaging2026
Prognostic significance of baseline
Article in BMC medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundPreoperative prognosis prediction is of significance for ampullary cancer patients. The prognostic factors of ampullary adenocarcinoma have been rarely studied, particularly the PET/CT metabolic parameters. This study aimed to investigate the prognostic significance of quantitative metabolic parameters on baseline
methodsThe clinical characteristics, histopathological features, and quantitative PET/CT parameters of ampullary adenocarcinoma patients were analyzed. Cox proportional hazard regression analyses were performed to identify independent predictors for tumor progression or patient survival. Progression free survival (PFS) and overall survival (OS) were evaluated using the Kaplan-Meier curves, and survival differences were compared using the log-rank test.
resultsThis retrospective study enrolled fifty-two ampullary adenocarcinoma patients (28 men, 24 women) with a median age of 64 years. The 1-year, 2-year, and 5-year PFS were 69.2%, 61.5%, and 59.6%, while OS were 90.4%, 78.8%, and 76.9%, respectively. Multivariate regression analyses revealed that the PET/CT volumetric parameter total lesion glycolysis (TLG) [hazard ratio (HR): 9.306, p < 0.001] and histologic differentiation grade (HR:3.477, p = 0.007) of the primary tumor lesion were predictive factors for PFS. Besides, TLG (HR:9.033, p = 0.046) and tumor size (HR:6.977, p = 0.018) were significant variables for predicting the OS.
conclusionsThe present study demonstrated that the PET volumetric parameter TLG of the primary tumor lesion emerged as a potential prognostic biomarker for PFS (together with histologic differentiation) and for overall survival (together with tumor size) of patients with ampullary adenocarcinoma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.