Evidence map›Paper›PMID 42728443›Full record

ArticleCurrent microbiology2026

Genomic Characterisation of Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter hormaechei Clinical Isolates from Nigeria: Evidence of Resistance, Virulence, and Putative Plasmid-Mediated Gene Sharing.

Sunday Babatunde Akinde, Ademola Ayodele Adesoye, Olabisi Olaniyi Ojo, Odunola Oluwaseun Oluwajide, Abideen Akinkunmi Wahab, Oluwaseyi Paul Olaniyan, Emmanuel Sunday Fajoyegbe, Inimary Toby-Ogundeji, Nusrah Bolatito Afolabi-Balogun, Omokaro Obire and 6 more

Abstract read
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Article in Current microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sunday Babatunde AkindeDepartment of Microbiology, Osun State University, Osogbo, Nigeria. akindesb@uniosun.edu.ng.
Ademola Ayodele AdesoyeDepartment of Microbiology, Osun State University, Osogbo, Nigeria.
Olabisi Olaniyi OjoDepartment of Natural Sciences, Albany State University, Albany, GA, USA.
Odunola Oluwaseun OluwajideDepartment of Science Laboratory Technology, Osun State University, Osogbo, Nigeria.
Abideen Akinkunmi WahabDepartment of Microbiology, Osun State University, Osogbo, Nigeria.
Oluwaseyi Paul OlaniyanMicrobial Biotechnology and One Health Research Laboratory, Osun State University, Osogbo, Nigeria.
Emmanuel Sunday FajoyegbeDepartment of Microbiology, Osun State University, Osogbo, Nigeria.
Inimary Toby-OgundejiBiology Department, University of Dallas, Irving, TX, USA.
Nusrah Bolatito Afolabi-BalogunMolecular Biology and Genetic Diversity Laboratory, Biochemistry Unit, Fountain University, Osogbo, Nigeria.
Omokaro ObireDepartment of Microbiology, Rivers State University, Port Harcourt, Nigeria.
Elijah Kolawole OladipoMolecular Biology, Immunology and Bioinformatics Laboratory, Department of Microbiology, Adeleke University, Ede, Nigeria.
Fatimah Adenike AjadiDepartment of Microbiology, Federal University of Health Sciences, Ila-Orangun, Nigeria.
Waidi Folorunso SuleDepartment of Microbiology, Osun State University, Osogbo, Nigeria.
Olasunbo Aina OlasupoDepartment of Microbiology, Osun State University, Osogbo, Nigeria.
Omotayo Opemipo OyedaraDepartment of Biotechnology, Osun State University, Osogbo, Nigeria.
Janet Olubukola OlaitanDepartment of Microbiology, Osun State University, Osogbo, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global proliferation of carbapenem-resistant Enterobacterales (CRE) constitutes one of the most urgent public health threats, yet high-resolution genomic data from sub-Saharan Africa remain critically scarce. We applied whole-genome sequencing (WGS) and comparative phylogenomics to characterise antimicrobial resistance determinants, virulence genes, and mobile genetic elements (MGEs) in three carbapenem-resistant clinical isolates originating from three tertiary hospitals (selected from a broader surveillance collection spanning four facilities) in Osun State, southwestern Nigeria. We purposively selected three isolates, two Klebsiella pneumoniae subsp. pneumoniae (K22, ST411; K31, ST17) and one Enterobacter hormaechei subsp. steigerwaltii (K32, ST45) from a broader surveillance collection of 27 carbapenem-non-susceptible Enterobacterales, to represent phenotypically and genotypically divergent lineages. Resistome analysis revealed extensive plasmid-associated β-lactam and aminoglycoside resistance in K31 (including bla

Indexed as

CarbapenemsEnterobacterEnterobacteriaceae InfectionsKlebsiella pneumoniaePlasmidsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesGenome, BacterialHumansMicrobial Sensitivity TestsNigeriaPhylogenyVirulenceWhole Genome SequencingAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenems

Identifiers

PMID42728443

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.