Evidence map›Paper›PMID 42728318›Full record

ArticleMolecular psychiatry2026

The psychiatric risk gene CACNA1C encodes distinct full-length isoforms in human brain, heart and aorta.

Nicola Al Hall, Arne W Mould, Isar Nassiri, Sofia Kudasheva, David J Wright, Li Chen, Osama A Arshad, Ran Tao, Joel E Kleinman, Daniel R Weinberger and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nicola Al HallDepartment of Psychiatry, University of Oxford, Oxford, UK. nicola.hall@psych.ox.ac.uk.ORCID http://orcid.org/0000-0002-3393-3494
Arne W MouldDepartment of Psychiatry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-2004-4348
Isar NassiriNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Sofia KudashevaEarlham Institute, Norwich, UK.ORCID http://orcid.org/0009-0003-6586-0933
David J WrightEarlham Institute, Norwich, UK.
Li ChenDepartment of Psychiatry, University of Oxford, Oxford, UK.
Osama A ArshadDepartment of Psychiatry, University of Oxford, Oxford, UK.
Ran TaoLieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.
Joel E KleinmanLieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-4210-6052
Daniel R WeinbergerLieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-2409-2969
Thomas M HydeLieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-8746-3037
Paul J HarrisonDepartment of Psychiatry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-6719-1126
Wilfried HaertyEarlham Institute, Norwich, UK.ORCID http://orcid.org/0000-0003-0111-191X
Elizabeth M TunbridgeDepartment of Psychiatry, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-2966-2281

Funding

DH | National Institute for Health Research (NIHR) NIHR203316RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/CCG1720/1RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BBS/E/ER/230001ARCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BBS/E/ER/230001CRCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BS/E/T/000PR981RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) NIHR203316
6 · The paper itself

Abstract

CACNA1C is a risk gene for multiple psychiatric disorders and the Ca

Identifiers

PMID42728318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.