Evidence map›Paper›PMID 42728250›Full record

ArticleScientific reports2026

Development and psychometric validation of SADAR-PrEP, an Indonesian PrEP knowledge and attitudes instrument.

Bustanul Arifin, Ayu Vinegia, Usmar Usmar, Sylmina Dalily Alkaff, Sri Awalia Febriana, Alessandro Alfieri, Saidah Rauf, Zulkarnain Zulkarnain, Dyah Aryani Perwitasari, Fredrick Dermawan Purba and 11 more

Abstract readValidation Study
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

21 authors.

Bustanul ArifinDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar, South Sulawesi, Indonesia. bustanul.arifin.ury@unhas.ac.id.
Ayu VinegiaDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar, South Sulawesi, Indonesia.
Usmar UsmarDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar, South Sulawesi, Indonesia.
Sylmina Dalily AlkaffRobotics and Artificial Intelligence, Department of Engineering, Faculty of Advanced Technology and Multidiscipline, Universitas Airlangga, Surabaya, Indonesia.
Sri Awalia FebrianaDepartment Dermatology and Venereology, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia/RSUP Dr. Sardjito, Yogyakarta, Indonesia.
Alessandro AlfieriDepartment Dermatology and Venereology, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia/RSUP Dr. Sardjito, Yogyakarta, Indonesia.
Saidah RaufPoliteknik Kesehatan Kemenkes Maluku, Ambon, Indonesia.
Zulkarnain ZulkarnainFaculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia, Thyroid Center, Zainoel Abidin Hospital, Banda Aceh, Indonesia.
Dyah Aryani PerwitasariFaculty of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Indonesia.
Fredrick Dermawan PurbaDepartment of Clinical and Health Psychology, Faculty of Psychology, Universitas Padjadjaran, Jatinangor, Indonesia.
Akhmad ArdiansyahDepartment of Pharmacy, Faculty of Science and Technology, Sembilanbelas November University, Kolaka, Southeast Sulawesi, Indonesia.
Firas Farisi AlkaffDivision of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Sovia SalamahDivision of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Susi Ari KristinaFaculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Latifah Mahaya SarifahLabuang Baji Hospital, Makassar, South Sulawesi, Indonesia.
Irnawati Hi AminHealth Office of North Maluku Province, Sofifi, North Maluku, Indonesia.
Fajar Wahyu PribadiFaculty of Medicine, Jenderal Soedirman University, Purwokerto, Indonesia.
Albert WertheimerNova Southeastern University, Ft. Lauderdale, FL, USA.
Maarten J PostmaUnit of Global Health, Department of Health Sciences, University of Groningen, University Medical Centre Groningen (UMCG), Ant. Deusinglaan 1, 9713 AV, Groningen, Netherlands.
Muhammad SyahrirFaculty of Public Health, Universitas Tompotika Luwuk, Banggai Regency, Central Sulawesi, Indonesia.
M Rifqi RokhmanUnit of Global Health, Department of Health Sciences, University of Groningen, University Medical Centre Groningen (UMCG), Ant. Deusinglaan 1, 9713 AV, Groningen, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of pre-exposure prophylaxis (PrEP) in Indonesia remains limited despite its proven effectiveness in HIV prevention, partly due to low public awareness and knowledge and the absence of validated measurement instruments for the general population. This study developed and psychometrically validated the SADAR-PrEP (Skala pengetAhuan DAn Respon terhadap PrEP) instrument through (i) forward-backward translation and cultural adaptation; (ii) content validity through multidisciplinary expert panel review (n = 25); (iii) face validity through structured cognitive interviews across regional groups; (iv) construct validity using exploratory factor analysis (EFA); (v) internal consistency reliability; and (vi) known-groups validity with effect sizes. A total of 1,150 adults from six regions in Indonesia completed the instrument. EFA revealed a unidimensional structure (KMO = 0.928; single factor eigenvalue = 4.959, explaining 49.6% of the variance; factor loadings 0.618-0.766). Internal consistency was excellent (Cronbach's α = 0.874; corrected item-total correlations 0.538-0.676). Known-groups comparisons confirmed significant differences in scores across education, health background, and workshop attendance groups (p ≤ 0.003; Cohen's d = 0.24-0.63). Although 74.3% expressed willingness to use PrEP, only 16.1% knew how to access services. SADAR-PrEP is the first validated PrEP knowledge and attitude instrument for the general Indonesian population, providing a scalable tool for evidence-based HIV prevention education, programme planning, and policy development.

Indexed as

Health Knowledge, Attitudes, PracticeHIV InfectionsPre-Exposure ProphylaxisPsychometricsAdultFemaleHumansIndonesiaMaleMiddle AgedReproducibility of ResultsSurveys and QuestionnairesYoung AdultHIV preventionIndonesiaInstrument validationKnowledge and attitudesPre-Exposure ProphylaxisSADAR-PrEP

Identifiers

PMID42728250
PMCPMC13569846

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.