ArticleResuscitation2026
Association of hypotension burden calculated from intermittently documented blood pressures and outcome after pediatric cardiac arrest.
Article in Resuscitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionHypotension burden measured using continuous high-resolution blood pressures (BPs) is associated with outcome following pediatric cardiac arrest. It is unclear whether this holds when using EHR-documented blood pressures, which are more available but measured differently. Our objective was to determine the association of hypotension burden calculated using EHR-documented BPs with outcome after pediatric cardiac arrest. Secondarily, we compared hypotension burden calculated using EHR-documented BPs vs. continuous high-resolution BPs.
methodsIn this single-center retrospective study, we quantified hypotension burden using EHR-documented BPs for 24 h following return of spontaneous circulation. We determined association of hypotension burden below the 10th percentile for age with unfavorable outcome (Pediatric Cerebral Performance Category Score ≥3 with change from pre-arrest) using logistic regression controlling for age, sex, arrest location, and lactate. Hypotension burden using EHR-documented BPs vs. continuous high-resolution BPs was compared with Bland-Altman analysis.
results139 patients were analyzed (median age 54 months, 60.7% male); 63% had unfavorable outcome. Using EHR-documented BPs, increasing burden of hypotension below 10th percentile-for-age was associated with greater odds of unfavorable outcome (odds ratio 4.64, 95% CI [1.21, 17.6], p = 0.025). Hypotension burden was similar when calculated using EHR-documented BPs vs. continuous high-resolution BPs (0.03 [0, 0.26] vs 0.04 [0, 0.38] mmHg-h, p = 0.165). There was no significant bias toward either measurement modality on Bland-Altman analysis (mean difference 0.22 ± 0.95, p = 0.096).
conclusionsHypotension burden calculated using EHR-documented BPs was associated with unfavorable outcome after pediatric cardiac arrest and closely approximated hypotension burden from continuous high-resolution BPs.
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