Evidence map›Paper›PMID 42727574›Full record

ArticleCell2026

Mitochondrial ATP promotes T cell differentiation through chromatin accessibility.

Charles Ng, Tak Shun Fung, Dayi Li, Korbinian N Kropp, Luis F Somarribas Patterson, Alexandria Markovitz, Daniel N Weinberg, Olivia Jones, Ji-Young Kim, Guoan Zhang and 17 more

Abstract read
PubMed Publisher
In one paragraph

Article in Cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Bringing CRISPR screens into tissue space.Nature reviews. Molecular cell biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Charles NgDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Tak Shun FungCancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Dayi LiCancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Korbinian N KroppImmuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Center for Cellular Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Luis F Somarribas PattersonHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Alexandria MarkovitzCancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Daniel N WeinbergCancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Olivia JonesProgram in Interdisciplinary Biological Sciences, Northwestern University, Evanston, IL, USA.
Ji-Young KimCancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Guoan ZhangProteomics and Metabolomics Core Facility, Weill Cornell Medicine, New York, NY, USA.
Richard KocheCenter for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mara MonettiProteomics and Metabolomics Core, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Huayuan TangInstitute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China.
Yun HeTranslational Innovation Center, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China.
Zhengshuang XuTranslational Innovation Center, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China.
Xin CaiDepartment of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, USA.
Ziqi YuCancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Geetha BhagavatulaDepartment of Medicine and the Mucosal Inflammation Program, University of Colorado School of Medicine, Aurora, CO, USA.
Sean P ColganDepartment of Medicine and the Mucosal Inflammation Program, University of Colorado School of Medicine, Aurora, CO, USA.
Ya-Hui LinHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Zhuoning LiProteomics and Metabolomics Core, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Elizabeth M SteinertDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Christopher A KlebanoffImmuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Center for Cellular Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Santosha A VardhanaHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Navdeep S ChandelDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Lin WuInstitute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China.
Craig B ThompsonCancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: thompsonc@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Exploring the Role of Nitrogen Metabolism in CancerR35CA283988 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CRAIG B THOMPSON · 2023 to 2026
$4.1M
Next-Gen Oncopathology ProgramT32CA260293 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Ethel Cesarman, BENJAMIN MONTEVERDE KLEAVELAND · 2022 to 2026
$1.4M
NCI NIH HHS P30 CA008748NCI NIH HHS R35 CA283988NCI NIH HHS T32 CA260293
6 · The paper itself

Abstract

Immune elimination of chronic infection or cancer requires cytotoxic CD8

Indexed as

BAFCD8 T cell effector functionchromatin remodelingcreatineD-alpha-hydroxybutyrateOXPHOSphosphocreatinetumor immunology

Identifiers

PMID42727574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.