Evidence map›Paper›PMID 42726679›Full record

ReviewOphthalmic research2026

Ocular Manifestations and Management of Graft-versus-Host Disease: A Comprehensive Review.

Sumana Chatterjee, Jaya Gupta, Shweta Agarwal, Jayanta Kuila, Vishal Jhanji, Namrata Sharma

Abstract readReview
In one paragraph

Review in Ophthalmic research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sumana ChatterjeeCornea and Ocular Surface, Sunayan Advanced Eye Institute, Tamluk, India, dr.sumanachatterjee@rediffmail.com.
Jaya GuptaCornea, Cataract and Refractive Surgery, The Healing Touch Superspeciality Eye Care Centre, New Delhi, India.
Shweta AgarwalCJ Shah Cornea Services, Sankara Nethralaya, Chennai, India.
Jayanta KuilaCataract and Retina Services, Sunayan Advanced Eye Institute, Tamluk, India.
Vishal JhanjiCornea Services, Professor of Ophthalmology, UPMC Vision Institute, University of Pittsburgh, Pittsburgh, USA.
Namrata SharmaCornea, Cataract and Refractive Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOcular graft-versus-host disease (oGVHD) is a critical complication following allogeneic haematopoietic stem cell transplantation, characterised by a T-cell-mediated immune response that results in inflammation and damage to various ocular structures. SUMMARY: While the ocular surface is primarily affected, oGVHD can also impact other eye components, leading to debilitating symptoms. The diagnosis of oGVHD poses significant challenges due to its relapsing and remitting nature, complicating effective treatment strategies. Prompt identification of ocular manifestations is essential, as early intervention can prevent vision-threatening complications and improve patient outcomes. As research continues to evolve, understanding the underlying mechanisms and exploring innovative therapeutic options will be crucial in managing this complex condition effectively. KEY MESSAGE: This review highlights the importance of heightened awareness among healthcare providers regarding the ocular signs of GVHD, advocating for timely diagnosis and personalised treatment approaches.

Indexed as

Disease ManagementEye DiseasesGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansAllo-HSCTCicatrising conjunctivitisCorneal ulcerDry eyesGraft-versus-host diseaseOcular GVHDPseudomembrane

Identifiers

PMID42726679
PMCPMC13685635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.