Evidence map›Paper›PMID 42726004›Full record

ArticleAntimicrobial agents and chemotherapy2026

Effectiveness of benznidazole in the treatment of Chagas disease in children and adults: a long-term retrospective cohort study.

A Rabinovich, C Cruz, G Moscatelli, S Moroni, N González, J C Ramirez, F Garcia-Bournissen, G Ballering, H Freilij, J Altcheh

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

A Rabinovich *Servicio de Parasitología and Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP), CONICET-GCBA, Hospital de Niños Ricardo Gutierrez, Buenos Aires, Argentina.ORCID 0000-0002-9291-9078
C Cruz *Division of Clinical Pharmacology and Toxicology, Department of Pediatrics, Sickkids, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-8393-8536
G MoscatelliServicio de Parasitología and Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP), CONICET-GCBA, Hospital de Niños Ricardo Gutierrez, Buenos Aires, Argentina.
S MoroniServicio de Parasitología and Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP), CONICET-GCBA, Hospital de Niños Ricardo Gutierrez, Buenos Aires, Argentina.
N GonzálezServicio de Parasitología and Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP), CONICET-GCBA, Hospital de Niños Ricardo Gutierrez, Buenos Aires, Argentina.
J C RamirezServicio de Parasitología and Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP), CONICET-GCBA, Hospital de Niños Ricardo Gutierrez, Buenos Aires, Argentina.
F Garcia-BournissenDivision of Paediatric Clinical Pharmacology, Department of Paediatrics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
G BalleringServicio de Parasitología and Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP), CONICET-GCBA, Hospital de Niños Ricardo Gutierrez, Buenos Aires, Argentina.
H FreilijServicio de Parasitología and Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP), CONICET-GCBA, Hospital de Niños Ricardo Gutierrez, Buenos Aires, Argentina.
J AltchehServicio de Parasitología and Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP), CONICET-GCBA, Hospital de Niños Ricardo Gutierrez, Buenos Aires, Argentina.ORCID 0000-0002-5865-7991

Funding

Wellcome Trust 222754/Z/21/Z
6 · The paper itself

Abstract

Chagas disease, caused by

Indexed as

Chagas DiseaseNitroimidazolesTrypanocidal AgentsTrypanosoma cruziAdultArgentinaChildChild, PreschoolFemaleHumansInfantMaleParasitemiaRetrospective StudiesTreatment OutcomeYoung AdultbenzonidazoleNitroimidazolesTrypanocidal AgentsadultsbenznidazoleChagas diseasechildrentreatmentTrypanosoma cruzi

Identifiers

PMID42726004
PMCPMC13689171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.