ArticleFrontiers in medicine2026
Intranodal palisaded myofibroblastoma of the supraclavicular region in an adolescent with an HDAC2 variant: a case report.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Intranodal palisaded myofibroblastoma (IPM) is a rare benign mesenchymal tumor of lymph nodes that most often arises in the inguinal region. We report an 18-year-old woman with an incidentally detected left supraclavicular mass. Imaging showed a well-circumscribed hypervascular lesion, and core biopsy demonstrated a spindle-cell neoplasm for which low-grade malignancy could not be excluded. Complete excision revealed an intranodal spindle-cell proliferation with nuclear palisading, hemorrhage, compressed peripheral lymphoid tissue, and hyalinized fibers. The morphology and immunophenotype supported IPM. Targeted sequencing identified an HDAC2 p.V12Sfs
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