ArticleTransplantation direct2026
Kidney Donation After Circulatory Death Is Associated With Sustained Graft Function, Comparable Graft, and Patient Survival.
Article in Transplantation direct, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Kidney transplantation is the preferred treatment for kidney failure, offering various benefits, yet donor supply remains limited worldwide, including in Australia and New Zealand. We examined long-term outcomes of kidney transplant recipients from donation after circulatory determination of death (DCDD) versus donation after neurological determination of death (DNDD) donors. Although DCDD kidneys carry a higher risk of delayed graft function (GF), long-term outcomes appear equivalent, but contemporary data on GF, particularly estimated glomerular filtration rate (eGFR), remain limited. Methods: Using the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, we included adult kidney-only transplant recipients from 2010 to 2023. Cox proportional hazards models assessed death-censored graft survival and patient survival (PS), linear mixed models evaluated GF (eGFR), and logistic regression examined acute rejection within 12 mo. Results: Among 10 144 recipients (DNDD n = 7406, DCDD n = 2738), death-censored graft survival did not differ between groups (adjusted hazard ratio [aHR] DCDD versus DNDD [aHR, 1.08; 95% confidence intervals (CI), 0.94-1.24; Conclusions: Despite a higher risk of early rejection, DCDD recipients had comparable graft and PS to DNDD recipients. Early GF improved rapidly in DCDD recipients and remained similar over time. These findings support the continued use of DCDD kidneys to expand the donor pool.
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Registered trials
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