Evidence map›Paper›PMID 42725168›Full record

ArticleAnnals of medicine and surgery (2012)2026

Trends in pediatric traumatic brain injury-related mortality in the United States from 1999 to 2024: a retrospective cross-sectional analysis.

Asad Ali Ahmed Cheema, Misbah Bibi, Zubia Usman, Abdul Moeez Awais, Zubair Ahmed, Eman Fatima, Fabeha Zafar, Muhammad Noshab

Abstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Asad Ali Ahmed CheemaDepartment of Medicine, International School of Medicine, International University of Kyrgyzstan, Bishkek, Kyrgyzstan.ORCID https://orcid.org/0009-0004-4664-591X
Misbah BibiDepartment of Medicine, Bahria University Medical and Dental College, Karachi, Pakistan.ORCID https://orcid.org/0009-0002-0793-7990
Zubia UsmanDepartment of Medicine, Punjab Medical College, Faisalabad, Pakistan.ORCID https://orcid.org/0009-0008-3490-7918
Abdul Moeez AwaisDepartment of Medicine, Islamic International Medical College, Riphah University, Rawalpindi, Pakistan.ORCID https://orcid.org/0009-0008-9948-4792
Zubair AhmedDepartment of Medicine, Shaikh Khalifa Bin Zayed Al Nahyan Medical and Dental College, Lahore, Pakistan.ORCID https://orcid.org/0009-0008-6617-9556
Eman FatimaDepartment of Medicine, Foundation University and Medical College, Islamabad, Pakistan.ORCID https://orcid.org/0009-0009-2675-631X
Fabeha ZafarDepartment of Medicine, Dow University of Health Sciences, Karachi, Pakistan.ORCID https://orcid.org/0009-0002-2732-0971
Muhammad NoshabDepartment of Medicine, International School of Medicine, International University of Kyrgyzstan, Bishkek, Kyrgyzstan.ORCID https://orcid.org/0009-0004-0240-9835

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pediatric traumatic brain injury (pTBI) remains a preventable cause of death among U.S. children and adolescents. Prior national CDC WONDER-based analyses described pTBI mortality through 2017; however, updated surveillance is needed to evaluate post-2017 and post-2020 trends. Methods: We conducted a population-based repeated cross-sectional analysis using the CDC WONDER Multiple Cause of Death data from 1999 to 2024 among U.S. residents aged 0-19 years with pTBI-related ICD-10 codes recorded anywhere on the death certificate. Crude mortality rates (CMRs) per 1 000 000 population were used to describe the absolute mortality burden. Joinpoint regression estimated the annual percent change (APC) and the average APC (AAPC). Results: From 1999 to 2024, 128 852 pTBI-related deaths occurred among individuals aged 0-19 years. Overall CMR declined from 89.78 per 1 000 000 population in 1999 to 46.63 per 1 000 000 population in 2024, with significant declines from 1999 to 2006 and from 2006 to 2010, a significant increase from 2013 to 2022, and no statistically significant change from 2022 to 2024. Males accounted for more deaths than females (91 852 vs. 37 000), and adolescents aged 15-19 years accounted for the largest number of deaths (82 409). Non-Hispanic American Indian or Alaska Native children had the highest annual CMRs in both bridged-race and single-race periods. State-level burden remained geographically heterogeneous, with Wyoming the highest and Massachusetts the lowest during 1999-2020, and Montana the highest and Massachusetts the lowest during 2021-2024. Conclusion: U.S. pTBI-related crude mortality burden declined overall from 1999 to 2024, but recent increases and persistent demographic and geographic differences highlight the need for continued surveillance and targeted prevention.

Indexed as

CDC WONDERjoinpoint regressionmortalitypediatric traumatic brain injuryUnited States

Identifiers

PMID42725168
PMCPMC13561252

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.