Evidence map›Paper›PMID 42725108›Full record

ArticleMaterials today. Bio2026

Metal-free nitroxide radical-based theranostic agent for MRI-guided therapy of ulcerative colitis.

Chunan Wang, Danfeng Peng, Ziwei Duan, Kai Jiang, Kai Wang, Xiaohui Duan, Lingjie Yang, Zhi Fang, Rui Guo, Dalin Wu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chunan WangSchool of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Danfeng PengSchool of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Ziwei DuanSchool of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Kai JiangSchool of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Kai WangSchool of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Xiaohui DuanDepartment of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
Lingjie YangDepartment of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
Zhi FangSchool of Materials, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Rui GuoGuangdong Provincial Engineering and Technological Research Center for Drug Carrier Development, Department of Biomedical Engineering, Jinan University, Guangzhou, 510632, China.
Dalin WuSchool of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Jie WangDongguan Liaobu Hospital, Dongguan, Guangdong, 523400, China.
Zhong CaoDongguan Liaobu Hospital, Dongguan, Guangdong, 523400, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional metal-based contrast agents for magnetic resonance imaging (MRI) present concerns regarding potential chronic toxicity with prolonged use and inherently lack therapeutic functionality. Integrating the antioxidant 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO), which possesses intrinsic paramagnetic properties, into nanocarriers presents a promising solution to these challenges. Herein, we synthesized a TEMPO-grafted block copolymer that self-assembles into nanoparticles encapsulating olsalazine (OS) to create TBATM@OS.

Indexed as

Metal-free MRI contrast agentsNano-theranostic agentTEMPO (2,2,6,6-tetramethylpiperidin-1-oxyl)Ulcerative colitis

Identifiers

PMID42725108
PMCPMC13560324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.