ArticleGland surgery2026
Influencing factors and prediction model of ultrasound-based false-negative central lymph node metastasis in localized papillary thyroid carcinoma.
Article in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Patients with papillary thyroid cancer (PTC) exhibited a high false-negative rate for central lymph nodes (CLNs), with unknown influencing factors and predictive models. This study aimed to identify risk factors for false-negative CLN findings in a cohort study and to develop a predictive model to support clinical decision-making. Methods: This cohort study included patients admitted to the Breast and Thyroid Surgery Department of Shandong Provincial Hospital, China, between January 2013 and December 2023. All patients included in the study were confirmed to papillary thyroid cancer (TC) based on postoperative paraffin-embedded pathology. False-negative CLNs refers to metastasis undetected by preoperative ultrasound but confirmed postoperatively by pathology. Logistic regression, forest graph and nomogram were used to calculate and display statistical difference between influencing factors and the false-negative rate of CLNs. Results: A total of 5,614 patients with papillary TC [44.19±11.14 years, 4,469 women (79.6%)] were analyzed. Logistic regression analysis showed that gender [odds ratio (OR): 1.832, 95% confidence interval (CI): 1.570-2.137, P<0.001], chronic disease (OR: 0.655, 95% CI: 0.552-0.778, P<0.001), diameter of malignant thyroid nodules under ultrasound (OR: 1.816, 95% CI: 1.511-2.182, P<0.001), diameter of CLNs under ultrasound (OR: 1.404, 95% CI: 1.074-1.836, P=0.01), enlargement of lateral lymph nodes (LLNs) under ultrasound (OR: 1.550, 95% CI: 1.213-1.980, P<0.001), diameter of LLN under ultrasound (OR: 0.645, 95% CI: 0.435-0.956, P=0.03) were statistically significant preoperative influencing factors. Conclusions: This cohort study indicated that the false-negative rate of CLNs was quite common. Personalized preventive CLN dissection was suggested.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.