ArticleTranslational cancer research2026
Association between primary tumor surgery and survival in patients with
Article in Translational cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The role of primary tumor surgery in patients with Methods: Female patients diagnosed with Results: A total of 1,827 patients were included, of whom 543 underwent primary tumor surgery and 1,284 did not. After 1:1 PSM, 507 matched pairs were generated. After matching, the median OS was 15 months in the surgery group and 9 months in the non-surgery group, while the median BCSS was 15 months and 10 months, respectively. In multivariable Cox analysis, primary tumor surgery was independently associated with longer OS [hazard ratio (HR) =0.532, 95% confidence interval (CI): 0.462-0.612, P<0.001] and BCSS (HR =0.544, 95% CI: 0.470-0.629, P<0.001). These associations remained stable in robust Cox sensitivity analyses. RMST analyses at 24 and 36 months further supported the robustness of the observed survival association. Conclusions: Primary tumor surgery was associated with longer OS and BCSS in patients with
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