Evidence map›Paper›PMID 42724646›Full record

ArticleBiophysics reports2026

Optical diffraction tomographic microscopy: a cutting-edge label-free three-dimensional bioimaging.

Junwei Min, Peng Gao, Xun Yuan, Yuge Xue, Ruihua Liu, Yingjie Feng, Siying Wang, Yan Li, Kai Wen, Liming Yang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Inverse-scattering of absorptive samples via beam propagation.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Junwei MinState Key Laboratory of Ultrafast Optical Science and Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
Peng GaoSchool of Physics, Xidian University, Xi'an 710071, China.
Xun YuanState Key Laboratory of Ultrafast Optical Science and Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
Yuge XueState Key Laboratory of Ultrafast Optical Science and Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
Ruihua LiuState Key Laboratory of Ultrafast Optical Science and Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
Yingjie FengState Key Laboratory of Ultrafast Optical Science and Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
Siying WangState Key Laboratory of Ultrafast Optical Science and Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
Yan LiState Key Laboratory of Ultrafast Optical Science and Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
Kai WenSchool of Physics, Xidian University, Xi'an 710071, China.
Liming YangState Key Laboratory of Ultrafast Optical Science and Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
Tengfei WuState Key Laboratory of Ultrafast Optical Science and Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
Baoli YaoState Key Laboratory of Ultrafast Optical Science and Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical diffraction tomographic microscopy (ODTM) is an advanced label-free three-dimensional optical microscopic imaging technique. It measures the three-dimensional refractive index (RI) distributions of unstained, transparent biological specimens with high resolution from scattered fields based on the diffraction tomography theorem. Both the morphological and biophysical parameters, as well as the internal organelles of the specimen, can be further analyzed from the measured RI values. ODTM has been increasingly employed in the field of biology, yielding numerous promising results. In order to further promote the application and popularization of this technology in biological research, we provide a tutorial on the fundamental principles and instrumentation of ODTM. The distinct characteristics of ODTM using various illumination strategies and reconstruction algorithms are presented. Observation results from single cells, tissues, and small-scale biological objects are shown to demonstrate the superior performance of ODTM. Current trends and future perspectives of ODTM are discussed.

Indexed as

Optical diffraction tomographyOptical microscopyQuantitative phase imagingRefractive index measurementThree-dimensional data reconstructionTomographic imaging

Identifiers

PMID42724646
PMCPMC13559529

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.