ArticleJournal of thoracic disease2026
Association between ambient temperature and acute type A aortic dissection in a Korean population: a 12-year dual-scale Poisson regression analysis.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Whether absolute temperature or day-to-day temperature fluctuation more strongly precipitates acute type A aortic dissection (ATAAD) remains unresolved, particularly in East Asian populations with distinct temperate-monsoon climates. This study investigated the association between meteorological factors and ATAAD occurrence in a Korean population over a 12-year period. Methods: Clinical data from 522 patients who underwent open surgical repair for ATAAD at a single tertiary center between January 2008 and December 2019 were retrospectively analyzed alongside meteorological data obtained from the Korea Meteorological Administration. Primary analyses focused on temperature variables-mean, lowest, and perceived (apparent) temperature on the day of onset and the previous day, as well as day-to-day temperature change-using Pearson correlation coefficients and Poisson regression models at both monthly and daily temporal scales. Results: ATAAD incidence demonstrated a marked winter predominance, peaking in December (n=65, 12.5%) and reaching its nadir in July (n=24, 4.6%); cold-season months (November-March) collectively accounted for 273 cases (52.3%). A strong negative correlation was observed between monthly ATAAD occurrence and all absolute temperature variables (r=-0.83 to -0.85, all P<0.001). Every 10 ℃ decrease in mean onset-day temperature was associated with a 26.8% increase in monthly incidence rate [incidence rate ratio (IRR): 1.268, 95% CI: 1.151-1.395, P<0.001] and a 7.4% increase in daily incidence rate (IRR 1.074, 95% CI: 1.012-1.139, P=0.02). Day-to-day temperature change was not significantly associated with ATAAD occurrence at either temporal scale (all P≥0.63). Conclusions: In a Korean population, lower absolute ambient temperature was significantly associated with increased ATAAD occurrence on both monthly and daily analyses, whereas day-to-day temperature fluctuation showed no statistically significant association. Heightened clinical awareness during cold seasons may contribute to earlier recognition and improved outcomes in high-risk patients.
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