Evidence map›Paper›PMID 42724504›Full record

ArticleAmerican journal of cancer research2026

Dual role of HIF-1α in gliomas: enhancing COX7A2 degradation and SCAF1 expression for ATP production and tumor progression.

Minfang Lai, Wenping Feng, Jinyou Ouyang, Jianguo Kuang, Shengze Deng

Abstract read
In one paragraph

Article in American journal of cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Minfang LaiDepartment of Pharmacy, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University Nanchang 330006, Jiangxi, China.
Wenping FengDepartment of Neurosurgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University Nanchang 330006, Jiangxi, China.
Jinyou OuyangDepartment of Neurosurgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University Nanchang 330006, Jiangxi, China.
Jianguo KuangDepartment of Neurosurgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University Nanchang 330006, Jiangxi, China.
Shengze DengDepartment of Neurosurgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University Nanchang 330006, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate whether HIF-1α promotes SCAF1/COX7A2 replacement in complex IV and thereby influences glioma progression.

methodsA172 and U251 cells were subjected to CoCl

resultsCoCl

conclusionHypoxia in glioma cells enhances cell viability, migration, invasion, ATP production, and I+III

Indexed as

ATP productionCOX7A2gliomaHypoxiaoxidative phosphorylationSCAF1

Identifiers

PMID42724504
PMCPMC13559315

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.