Evidence map›Paper›PMID 42724316›Full record

ArticleJournal of thoracic disease2026

Prognostic value of the 11-factor modified frailty index for early postoperative outcomes in elderly lung transplant recipients: a retrospective cohort study.

Zeyong Zhang, Qimei Liang, Kaishan Ouyang, Huiru Cao, Danli Li, Guanxiang Luo, Dongyun Qing, Qianying Zhang, Jingjuan Huang

Abstract read
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Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Zeyong Zhang *Operating Room, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Qimei Liang *Operating Room, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Kaishan Ouyang *Operating Room, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Huiru CaoOperating Room, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Danli LiOperating Room, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Guanxiang LuoOperating Room, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Dongyun QingOperating Room, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Qianying ZhangOperating Room, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Jingjuan HuangOperating Room, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0001-6940-8811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Frailty is increasingly recognized as a key determinant of surgical outcomes, yet few data describe the prognostic value of the 11-factor modified frailty index (mFI-11) in elderly lung transplant recipients. We aimed to assess the prognostic value of mFI-11 for early postoperative outcomes, including 30- and 90-day mortality and major complications in elderly lung transplant recipients. Methods: We conducted a retrospective cohort study of patients aged ≥65 years who underwent lung transplantation at The First Affiliated Hospital of Guangzhou Medical University between September 2019 and January 2025. mFI-11 scores were calculated from 11 preoperative comorbidities/functional impairments; frailty was defined as mFI-11 ≥3. Uni- and multivariable regression models were used to examine associations between frailty and 30- and 90-day mortality, postoperative complications, and intensive care unit (ICU) hospital length of stay (LOS). Results: Among 144 elderly recipients, 69 (47.9%) were frail. Frail patients had significantly higher 90-day mortality (33.33% Conclusions: mFI-11 is a clinically significant predictor of early mortality and postoperative complications in elderly lung transplant recipients and may support risk stratification and targeted perioperative management.

Indexed as

11-factor modified frailty index (mFI-11)elderly patientsFrailty Indexlung transplantationpostoperative complication

Identifiers

PMID42724316
PMCPMC13559294

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