SynthesisFrontiers in public health2026
Population-level association of layperson cardiopulmonary resuscitation training with survival after out-of-hospital cardiac arrest: a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Out-of-hospital cardiac arrest (OHCA) is a significant worldwide cause of death and is highly dependent upon bystander intervention. Layperson cardiopulmonary resuscitation (CPR) training has been widely promoted, but its population-level association with survival after out-of-hospital cardiac arrest remains incompletely characterized. Methods: This systematic review and meta-analysis was conducted according to PRISMA guidelines and registered in PROSPERO. PubMed, Embase, Web of science and Cochrane Library and major Chinese database were searched from inception to June 1, 2026. Studies evaluating the association between layperson CPR training and OHCA survival outcomes were included. The main outcome measure was survival to hospital discharge. Random-effects models were used for calculation of pooled odds ratios (ORs) and 95% confidence intervals (CIs). I Results: Nineteen observational studies comprising 159,378 participants from eight countries were included in the systematic review. Seventeen studies comprising 144,775 participants contributed to the training-modality-specific meta-analyses. Layperson CPR training was associated with higher survival to hospital discharge. In the training-modality-specific analyses, favorable associations were observed for both CPR-only training (OR = 1.74, 95% CI: 1.39-2.19) and CPR combined with AED training (OR = 1.42, 95% CI: 1.15-1.77). There was evidence of significant heterogeneity among the studies, but no evidence of publication bias. Conclusion: Layperson CPR training was associated with higher population-level survival after OHCA and should be viewed as one component of an integrated community resuscitation system. Systematic review registration: https://www.crd.york.ac.uk/prospero/record_view.phprecid=CRD420261479204.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.