ArticleFrontiers in oncology2026
Hypothermia and recovery outcomes before and after implementation of a multimodal perioperative temperature-management bundle in minimally invasive radical rectal cancer surgery.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Background: Inadvertent perioperative hypothermia is common during minimally invasive rectal cancer surgery. We assessed whether a five-component multimodal temperature-management bundle was associated with improved perioperative outcomes. Methods: This single-center retrospective before-and-after study included 247 adults undergoing laparoscopic or robot-assisted radical rectal cancer surgery from 2021 to 2025 (pre-implementation, n = 123; post-implementation, n = 124). The primary outcome was any intraoperative nasopharyngeal core temperature <36.0 °C. Key secondary outcomes were minimum temperature, cumulative hypothermia duration, postanesthesia care unit (PACU) stay, shivering, and 30-day composite complications. Prespecified mixed-effects and multiplicity-adjusted analyses were performed. Results: Hypothermia occurred in 84/123 patients (68.3%) before implementation and 19/124 (15.3%) after implementation (absolute risk difference, -53.0 percentage points; 95% confidence interval [CI], -62.2 to -41.6; Conclusions: Bundle implementation was associated with lower intraoperative hypothermia burden and improved selected recovery outcomes. The nonrandomized calendar-period design and possible secular confounding limit causal interpretation.
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