ArticleFrontiers in oncology2026
Müllerian clear cell carcinoma arising from sigmoid endometriosis with pericolic lymph node metastasis in the absence of adnexal disease: a case report.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Editorial Comment to Paraurethral Endometrioid Carcinoma Arising From Ectopic Endometriosis: A Case Report.IJU case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Malignant transformation of endometriosis is rare and most commonly involves the ovary. Extraovarian transformation, particularly in the gastrointestinal tract, is exceptional, and clear cell carcinoma (CCC) arising from intestinal endometriosis is rarely reported. Case presentation: We report a 64-year-old postmenopausal woman with no prior history of endometriosis in whom a sigmoid lesion was incidentally detected during follow-up for a presumed benign ovarian cyst. Colonoscopic biopsy revealed a poorly differentiated carcinoma with clear cell features, and immunohistochemistry (PAX8+, CK7+, HNF1β+, CK20-) supported a Müllerian origin. The patient underwent complete cytoreductive surgery (R0). Final histology confirmed Müllerian clear cell carcinoma arising from sigmoid endometriosis with pericolic lymph node metastasis (pT3N1M0). Integration of the immunophenotypic profile (PAX8+, CK7+, HNF1β+, CK20-), and demonstration of adjacent endometriosis supported the diagnosis of Müllerian clear cell carcinoma arising from endometriosis, fulfilling the Sampson and Scott criteria. She received adjuvant carboplatin and paclitaxel and is disease-free at 6 months. Conclusion: Müllerian CCC arising from intestinal endometriosis is extremely rare and may occur in postmenopausal women without known endometriosis. Accurate immunohistochemical diagnosis is essential to avoid misclassification and guide appropriate oncologic management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.