ArticleFrontiers in medicine2026
Structured clinical adjudication of
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
Background: Lower respiratory tract infections developing during invasive mechanical ventilation in patients with severe COVID-19 acute respiratory distress syndrome (ARDS) present important diagnostic and therapeutic challenges. Case presentation: A 65-year-old woman with hypertension and obesity was admitted with severe COVID-19 ARDS requiring invasive mechanical ventilation after failure of high-flow nasal cannula. Baseline laboratory evaluation demonstrated leukocytosis (15.65 × 10 Conclusion: This case illustrates the application of a structured clinical adjudication process to interpret recovery of an uncommon respiratory microorganism under conditions of microbiological uncertainty. Integration of quantitative bronchoalveolar lavage culture, rapid multiplex PCR, host factors, radiological assessment, and clinical evolution may support antimicrobial optimization while avoiding overinterpretation of uncommon respiratory isolates. The proposed approach should be regarded as an educational and descriptive clinical illustration requiring evaluation in future studies.
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