Evidence map›Paper›PMID 42723863›Full record

ArticleFrontiers in dental medicine2026

Rare mandibular metastasis of neuroblastoma in a child: a case report.

Safaa El Omari, Malika Afif, Sana Bensouda, Samira El Arabi

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In one paragraph

Article in Frontiers in dental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Safaa El OmariDepartment of Pediatric Dentistry, Faculty of Dentistry, Hassan II University, Casablanca, Morocco.
Malika AfifDepartment of Pediatric Dentistry, Faculty of Dentistry, Hassan II University, Casablanca, Morocco.
Sana BensoudaDepartment of Pediatric Dentistry, Faculty of Dentistry, Hassan II University, Casablanca, Morocco.
Samira El ArabiDepartment of Pediatric Dentistry, Faculty of Dentistry, Hassan II University, Casablanca, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although neuroblastoma is a common malignant tumor in children and distant metastases are frequently observed, involvement of the mandible remains rare. We report the case of a 7-year-old boy presenting with a right mandibular mass associated with an oral lesion in the region of tooth 46, suggestive of a secondary lesion. Histopathological examination of the biopsy specimen confirmed the diagnosis, whereas imaging initially suggested lymphoma, soft tissue sarcoma, or osteosarcoma. Staging work-up revealed an adrenal neuroblastoma with multiple bone metastases. Given the extent of tumor involvement and the advanced stage of the disease, palliative chemotherapy was initiated. The clinical course was unfavorable, marked by the development of additional disseminated metastases, leading to the patient's death 14 months after the diagnosis of mandibular metastasis. This case highlights the importance of early multidisciplinary collaboration between pediatric dentistry and pediatric oncology teams to optimize diagnostic and therapeutic management in such patients.

Indexed as

case reportmandibular metastasisneuroblastomaoral lesionpediatric oncology

Identifiers

PMID42723863
PMCPMC13558099

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.