ArticleHRB open research2025
Greater occipital nerve stimulation for cognitive impairment in Parkinson's disease: A two-stage feasibility and tolerability study.
Article in HRB open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Background: Effective treatments for cognitive impairment in Parkinsons's disease (PD) are needed, with Greater Occipital Nerve Stimulation (GONS) emerging as a potential therapeutic approach. This study aimed to explore PD patients' attitudes toward GONS and assess its safety and tolerability in an open-label field study. Methods: A two-stage study was carried out, comprising an online survey to gather self-reported attitudes from individuals with PD toward GONS as a treatment option, followed by an open-label field study evaluating the safety, tolerability, and acceptability of GONS in PD-MCI patients. Results: Of 50 survey participants, 86% expressed willingness to try GONS for cognitive impairment. Five participants completed the GONS intervention, which was found to be safe, well-tolerated, and acceptable. Conclusion: People with PD are open to novel interventions for cognitive impairment. GONS was shown to be safe and well-tolerated, warranting further investigation as a potential therapeutic approach.
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