Eco-Friendly Pectin-Derived Heterocycles as Potent Larvicides: Biochemical and Insecticidal Insights Against Culex pipiens With Computational Investigation.

Asmaa M Fahim, Mostafa E Salem, Omina M H M Kamal

Abstract read

In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Asmaa M FahimDepartment of Green Chemistry, National Research Centre, Cairo, Egypt.ORCID https://orcid.org/0000-0002-0293-3491

Mostafa E SalemDepartment of Chemistry, College of Science, Imam Mohammad, Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0003-4341-410X

Omina M H M KamalDepartment of Applied Organic Chemistry, Industrial Chemistry Research Institute, National Research Center, Cairo, Egypt.ORCID https://orcid.org/0000-0003-0344-2472

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mosquito-borne diseases remain a public-health concern, creating an urgent need for safer and biodegradable alternatives to conventional insecticides. In this study, pectin was chemically modified to prepare pectin hydrazide, pectin oxadiazole, and pectin triazole derivatives as eco-friendly heterocyclic biopolymer-based larvicides. Structural modification was confirmed by spectroscopic, thermal, and morphological characterization. Larvicidal activity was evaluated against third-instar Culex pipiens larvae after 24 and 48 h of exposure. Mortality increased in a concentration- and time-dependent manner, with pectin hydrazide showing the highest activity after 48 h and an LC

Indexed as

CulexHeterocyclic CompoundsInsecticidesPectinsAnimalsGlutathione TransferaseLarvaMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructureStructure-Activity RelationshipGlutathione TransferaseHeterocyclic CompoundsInsecticidesPectinsATPase inhibitionbiochemical assayscomputational analysisCulex pipienseco‐friendly insecticidesglutathione S‐transferase (GST)larvicidal activitypectin derivatives

Identifiers

PMID42723247

DOI10.1002/cbdv.71613

PMCPMC13562833

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.