Evidence map›Paper›PMID 42723157›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Carbohydrate-Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin-Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM.

Haobo Ge, John S Fossey, David Gonzalez Calatayud, Stephen E Flower, Sabrina Wang, Hanna Aitessaid, Melita Tvardauskaite, Julia Dudzic, Max Jewell, Charareh Pourzand and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Haobo GeDepartment of Chemistry, University of Bath, Bath, UK.
John S FosseyDepartment of Chemistry, University of Bath, Bath, UK.ORCID https://orcid.org/0000-0002-2626-5117
David Gonzalez CalatayudDepartment of Inorganic Chemistry, Universidad Autónoma de Madrid, Madrid, Spain.ORCID https://orcid.org/0000-0003-2633-2989
Stephen E FlowerDepartment of Chemistry, University of Bath, Bath, UK.ORCID https://orcid.org/0000-0003-2659-3118
Sabrina WangDepartment of Chemistry, University of Bath, Bath, UK.
Hanna AitessaidDepartment of Life Sciences, University of Bath, Bath, UK.
Melita TvardauskaiteDepartment of Life Sciences, University of Bath, Bath, UK.
Julia DudzicDepartment of Life Sciences, University of Bath, Bath, UK.
Max JewellDepartment of Chemistry, University of Bath, Bath, UK.
Charareh PourzandDepartment of Life Sciences, University of Bath, Bath, UK.ORCID https://orcid.org/0000-0002-9046-1155
Stanley W BotchwayCentral Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, Oxfordshire, Didcot, UK.
David GurevichDepartment of Life Sciences, University of Bath, Bath, UK.
Tony D JamesDepartment of Chemistry, University of Bath, Bath, UK.ORCID https://orcid.org/0000-0002-4095-2191
Sofia I PascuDepartment of Chemistry, University of Bath, Bath, UK.ORCID https://orcid.org/0000-0001-6385-4650

Funding

ERC Consolidator Grant O2Sense 617107ERC PoC Tools-To-Sense 963937Wellcome TrustWellcome Trust Sir Henry Dale fellowship 220188/A/20/Z
6 · The paper itself

Abstract

Understanding how synthetic molecular probes interact with biological carbohydrates is essential for theranostics design and discovery. We report new supramolecular polysaccharide complexes, comprising simultaneously functionalised boronic acids conjugated to xanthate-based fluorescent tags bound to saccharides such as glucose or β-D-glucan (a natural product from Hordeum Vulgare). These hybrids were investigated in solution and in the cellular milieu using advanced biophysical methods, including multiphoton fluorescence lifetime imaging microscopy (MP-FLIM). A new type of fluorescent hybrid nanoparticle was also generated by conjugating boronic acids to ─Si(OH)

Indexed as

biochemistrybiophysicsboronic acidchemistryconfocalfluorescence microscopelive cell imagingzebrafish

Identifiers

PMID42723157
PMCPMC13562794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.