Evidence map›Paper›PMID 42722728›Full record

ArticlePediatric research2026

Immersive reality training for gross motor outcomes in children with Down syndrome.

Nilla Mayasari, Irawan Yusuf, Nadirah Rasyid Ridha, Andi Alfian Zainuddin, Yose Waluyo, Sri Mardjiati Mei Wulan, Firdaus Hamid

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Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Nilla MayasariDepartment of Physical Medicine and Rehabilitation, Dr. Wahidin Sudirohusodo General Hospital, Makassar, Indonesia. nillamayasari@unhas.ac.id.
Irawan YusufDepartment of Physiology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Nadirah Rasyid RidhaDepartment of Pediatrics, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Andi Alfian ZainuddinDepartment of Public Health, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Yose WaluyoDepartment of Physical Medicine and Rehabilitation, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Sri Mardjiati Mei WulanDepartment of Physical Medicine and Rehabilitation, Faculty of Medicine, Airlangga University, Surabaya, Indonesia.
Firdaus HamidDepartment of Microbiology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGross motor delays are common in children with Down syndrome (DS) and may limit participation. Immersive reality-based training may support motor learning through interactive, task-oriented practice and multisensory feedback, but evidence in children with DS remains limited.

methodsIn this pilot randomized study, 10 children with DS were allocated to immersive reality-based training (n = 5) or conventional training (n = 5). All participants were 10 years old, with varying cognitive ages. Both groups received supervised motor training twice weekly for 6 weeks. Standardized gross motor outcomes were assessed using the Test of Gross Motor Development-2 at baseline, during intervention, post-intervention, and follow-up.

resultsAll participants completed the intervention and follow-up, with 100% session attendance and no adverse events. Gross Motor Quotient improved in both groups, from 52.60 ± 4.93 to 75.40 ± 4.93 in the immersive reality group and from 61.60 ± 5.77 to 75.40 ± 2.51 in the conventional group. Gross Motor Quotient change was greater in the immersive reality group.

conclusionsImmersive reality-based training was feasible, well tolerated, and associated with improved standardized gross motor outcomes. Findings require cautious interpretation because of the small sample size and baseline imbalance. IMPACT: Immersive reality-based training was feasible and well tolerated in children with Down syndrome, with complete session attendance and no adverse events. Both immersive reality-based and conventional training were associated with improvements in standardized TGMD-2 outcomes over time. The immersive reality group showed greater absolute improvement in Gross Motor Quotient, although findings should be interpreted cautiously because of the small sample size and baseline imbalance. This pilot randomized study supports larger trials evaluating immersive reality-based training as a complementary modality in pediatric motor rehabilitation.

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.