Evidence map›Paper›PMID 42722645›Full record

ArticleNature communications2026

The metabolic and anatomical complexity of root microhabitats modulate their interaction with the microbiota.

Juan P Frene, Valéria Custódio, Helena Rouco, Sandra Martinez-Jarquin, Yi-Qun Gao, Vincenzo di Bari, Niokhor Bakhoum, Trent R Northen, Benjamin P Bowen, Katherine B Louie and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Juan P FreneSchool of Biosciences, University of Nottingham, Sutton Bonington, UK.ORCID http://orcid.org/0000-0001-7754-1591
Valéria CustódioSchool of Biosciences, University of Nottingham, Sutton Bonington, UK.
Helena RoucoSchool of Pharmacy, University of Nottingham, Nottingham, UK.
Sandra Martinez-JarquinSchool of Pharmacy, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0002-4908-8934
Yi-Qun GaoSchool of Biosciences, University of Nottingham, Sutton Bonington, UK.
Vincenzo di BariSchool of Biosciences, University of Nottingham, Sutton Bonington, UK.
Niokhor BakhoumSchool of Biosciences, University of Nottingham, Sutton Bonington, UK.ORCID http://orcid.org/0000-0002-2533-3405
Trent R NorthenDOE Joint Genome Institute, Lawrence Berkeley National Lab, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-5903-1870
Benjamin P BowenDOE Joint Genome Institute, Lawrence Berkeley National Lab, Berkeley, CA, USA.ORCID http://orcid.org/0000-0003-1368-3958
Katherine B LouieDOE Joint Genome Institute, Lawrence Berkeley National Lab, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-6787-7558
Katerina VelchovaSchool of Biosciences, University of Nottingham, Sutton Bonington, UK.ORCID http://orcid.org/0000-0001-8059-212X
Alexander WareSchool of Biosciences, University of Nottingham, Sutton Bonington, UK.
Anthony BishoppSchool of Biosciences, University of Nottingham, Sutton Bonington, UK.
Alvaro MataSchool of Pharmacy, University of Nottingham, Nottingham, UK.ORCID http://orcid.org/0000-0002-6739-9111
Gabriel CastrilloSchool of Biosciences, University of Nottingham, Sutton Bonington, UK. gabriel.castrillo@nottingham.ac.uk.ORCID http://orcid.org/0000-0002-1557-6614

Funding

Human Frontier Science Program (HFSP) RGP005/2024RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) UKRI755
6 · The paper itself

Abstract

Plant roots constantly communicate with their microbiota, adapting their anatomy to facilitate microbial colonisation under abiotic stresses. Microbes, in turn, can reshape root anatomy once they establish. However, the mechanisms that coordinate this interplay remain largely unknown. Working with the aquatic plant family Lemnaceae, we reveal that the inherent complexity of root anatomy determines root plasticity in response to microbial colonisation. This microbiota-driven anatomical plasticity enhances plant survival in nutrient-competitive environments. By combining synthetic root models with real roots, we also find that anatomical plasticity is associated with metabolic reprogramming during microbial establishment. Moreover, we identify a plant metabolite, N

Indexed as

MicrobiotaPlant RootsEcosystemLysineStress, PhysiologicalLysine

Identifiers

PMID42722645
PMCPMC13562559

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.