Evidence map›Paper›PMID 42722385›Full record

ArticleEmergency medicine Australasia : EMA2026

Local Anaesthetic Dosing and Toxicity Knowledge in Australian Emergency Departments: A Multicentre Cross-Sectional Survey.

Andrew Follows, Ben Rose, Andrew Ross, Abby McCaughey

Abstract readMulticenter Study
In one paragraph

Article in Emergency medicine Australasia : EMA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew FollowsMetro North Health, Brisbane, Queensland, Australia.ORCID https://orcid.org/0009-0000-2828-9887
Ben RoseMetro North Health, Brisbane, Queensland, Australia.ORCID https://orcid.org/0009-0005-6686-9985
Andrew RossMetro North Health, Brisbane, Queensland, Australia.ORCID https://orcid.org/0009-0008-7142-4675
Abby McCaugheyMetro North Health, Brisbane, Queensland, Australia.ORCID https://orcid.org/0009-0009-8658-9189

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLocal anaesthetic systemic toxicity (LAST) is a rare but potentially fatal complication of local anaesthetic (LA) use. This study assessed knowledge of LA dosing, LAST recognition and management among emergency clinicians in Australia.

methodsA multicentre cross-sectional survey was conducted at three emergency departments in Queensland, Australia. The survey assessed recall knowledge of recommended maximum local anaesthetic doses, recognition and management of LAST, and self-reported clinician confidence.

resultsOf 114 participating clinicians, fewer than half correctly identified the recommended maximum dose for any of the four evaluated LA agents, including for their preferred agent for regional anaesthetic techniques. Correct responses ranged from 18.4% for bupivacaine to 48.2% for lidocaine. Cardiovascular manifestations of LAST were the most frequently recognised features; 21.9% of respondents could not recall any features of LAST. 57.9% of respondents identified lipid emulsion therapy as a management strategy; however, only 10.5% correctly stated a dosing regimen and 6.1% knew its location within their department. Knowledge of doses, LAST recognition and management all significantly improved with clinician seniority. Self-reported confidence was positively associated with knowledge of LAST recognition and management.

conclusionsEmergency clinicians in this survey demonstrated substantial knowledge gaps in safe LA dosing, LAST recognition and aspects of management. These findings support a need for targeted education and system-level interventions to improve preparedness for this potentially life-threatening emergency.

Indexed as

Anesthetics, LocalClinical CompetenceEmergency Service, HospitalHealth Knowledge, Attitudes, PracticeAustraliaCross-Sectional StudiesFemaleHumansMaleQueenslandSurveys and QuestionnairesAnesthetics, Localcross‐sectional surveyemergency medicinelocal anaestheticlocal anaesthetic systemic toxicity

Identifiers

PMID42722385
PMCPMC13561662

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.