Evidence map›Paper›PMID 42721829›Full record

ArticleBrazilian journal of physical therapy2026

Effectiveness of photobiomodulation therapy associated with multimodal therapeutic intervention program versus multimodal therapeutic intervention program in chronic non-specific neck pain: A randomized controlled trial.

Aron Charles Barbosa da Silva, Gabriela Nascimento de Santana, Patrícia Gabrielle Dos Santos, Carlos Eduardo Girasol, Adriano Rodrigues de Oliveira, Almir Vieira Dibai-Filho, Cid André Fidelis-De-Paula-Gomes

Abstract read
In one paragraph

Article in Brazilian journal of physical therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aron Charles Barbosa da SilvaPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, São Paulo, SP, Brazil. Electronic address: charlesmam43@gmail.com.
Gabriela Nascimento de SantanaPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, São Paulo, SP, Brazil.
Patrícia Gabrielle Dos SantosPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, São Paulo, SP, Brazil.
Carlos Eduardo GirasolDepartment of Physiotherapy, Universidade do Estado de Santa Catarina, Florianópolis, Brazil.
Adriano Rodrigues de OliveiraPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, São Paulo, SP, Brazil.
Almir Vieira Dibai-FilhoPostgraduate Program in Physical Education, Federal University of Maranhão, São Luís, Brazil.
Cid André Fidelis-De-Paula-GomesPostgraduate Program in Rehabilitation Sciences, Nove de Julho University, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhotobiomodulation therapy (PBMT) has shown benefits for musculoskeletal disorders, but its additive effects when combined with the Multimodal Therapeutic Intervention Program (MTIP) in chronic nonspecific neck pain (CNSNP) remain uncertain.

objectiveTo compare the effectiveness of PBMT combined with an MTIP on functional capacity, pain intensity, catastrophizing, and kinesiophobia in individuals with CNSNP.

methodsThis was a two-arm, parallel, single-blind, superiority randomized controlled trial. Sixty-two participants with CNSNP were randomly allocated to either PBMT+MTIP or MTIP only. Both groups received an 8-week MTIP program; only the experimental group received additional infrared laser PBMT. The primary outcome was functional disability (Neck Disability Index). Secondary outcomes included pain intensity at rest and during movement (Numerical Pain Rating Scale), catastrophizing (Pain-Related Catastrophizing Thoughts Scale), kinesiophobia (Tampa Scale for Kinesiophobia), functional disability (Copenhagen Neck Functional Disability Scale), and global perceived effect. Outcomes were assessed at baseline, post-intervention, and one-month follow-up. Linear mixed models were used for analysis.

resultsFifty-six participants completed the 8-week follow-up, and fifty-two completed the 1-month follow-up. Statistically significant differences favoring the MTIP group were found in functional disability post-intervention (4.06, 95% CI 2.83 to 5.28) and at the one-month follow-up (3.23, 95% CI 1.97 to 4.48). Pain intensity at rest also showed statistically significant differences favoring the MTIP group post-intervention (0.54, 95% CI 0.14 to 0.95) and at the one-month follow-up (0.79, 95% CI 0.37 to 1.21).

conclusionUnder the specific PBMT dosage conditions, adding PBMT to MTIP did not yield further improvements over MTIP alone in individuals with CNSNP.

Indexed as

Chronic nonspecific neck painExercise therapyManual therapyPain managementPhotobiomodulation therapyRehabilitation

Identifiers

PMID42721829
PMCPMC13584099

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.