ArticleJournal of applied physiology (Bethesda, Md. : 1985)2026
Endoscopic sympathectomy impairs forearm cutaneous vascular conductance and sweating responses during passive whole body heat stress.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Hyperhidrosis is characterized by excessive sweating, typically in the palmar and axillary regions. Individuals with severe cases of hyperhidrosis can be treated surgically via endoscopic thoracic sympathectomy to disrupt the neural connection between the spinal cord and the affected regions, thereby attenuating sweating in the hyperhidrotic regions. However, the effects of this procedure on skin blood flow and sweating responses to whole body heat stress in regions not targeted by the sympathectomy, such as the forearm, are unknown. We tested the hypothesis that surgical sympathectomy attenuates the increase in forearm cutaneous vascular conductance and sweating during whole body heat stress. Before and 7 ± 1 wk following bilateral thoracic surgical sympathectomy, forearm skin blood flow (laser-Doppler imaging) and local sweat rate (capacitance hygrometry) were assessed during whole body passive heat stress sufficient to elevate core temperature by ∼1°C (
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