Evidence map›Paper›PMID 42720514›Full record

ArticleAnnals of medicine2026

Secondary hypoalbuminemia is independently associated with in-hospital mortality in children with

Jie Cheng, Ya Liu, Shaojun Li, Hongdong Li, Junming Huo, Liping Tan, Zhengxiu Luo

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Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jie ChengDepartment of Emergency, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Ya LiuDepartment of Pediatrics, Chongqing Youyoubaobei Women and Children's Hospital, Chongqing, China.
Shaojun LiDepartment of Emergency, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Hongdong LiDepartment of Emergency, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Junming HuoIntelligent Application of Big Data in Pediatrics Engineering Research Center of Chongqing Education Commission of China, Chongqing, China.
Liping TanDepartment of Emergency, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Children and Adolescents' Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Zhengxiu LuoIntelligent Application of Big Data in Pediatrics Engineering Research Center of Chongqing Education Commission of China, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHypoalbuminemia is common in critically ill children, however, its prognostic role in pediatric

methodsWe retrospectively enrolled 211 children with

resultsIn-hospital mortality was 12.32% (26/211). Secondary hypoalbuminemia after BSI occurred in 10.90% (23/211). Multivariable analysis identified four factors independently associated with in-hospital mortality: invasive mechanical ventilation (OR 46.40, 95% CI 3.90-552.62), secondary hypoalbuminemia (OR 10.59, 95% CI 1.39-80.91), higher PRISM III score (OR 1.18, 95% CI 1.03-1.36), and shorter time to positivity (TTP) (OR 0.71 per hour increase, 95% CI 0.56-0.89; i.e. shorter TTP was associated with higher mortality); all

conclusionsSecondary hypoalbuminemia developing after

Indexed as

BacteremiaEscherichia coli InfectionsHospital MortalityHypoalbuminemiaChildChild, PreschoolEscherichia coliFemaleHumansInfantKaplan-Meier EstimateMalePrognosisRetrospective StudiesRisk FactorsBloodstream infectionchildrenEscherichia colimortalitySecondary hypoalbuminemia

Identifiers

PMID42720514
PMCPMC13564163

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.