Evidence map›Paper›PMID 42720183›Full record

ArticleGeobiology

Origins of Improved Hardness in Bioinspired Aragonite Precipitated Under Simulated Biologic Conditions.

Boontharee Chomhom, Gabriela A Farfan, Samantha Greeves, Kirsty Penkman, Adrian A Finch, Susan Fitzer, Roland Kröger, Alex Brasier, John Still, Matthieu Clog and 1 more

Abstract read
In one paragraph

Article in Geobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Boontharee ChomhomSchool of Earth and Environmental Sciences, University of St Andrews, St Andrews, UK.ORCID https://orcid.org/0009-0001-5127-3397
Gabriela A FarfanDepartment of Mineral Sciences, National Museum of Natural History, Smithsonian Institution, Washington, DC, USA.ORCID https://orcid.org/0000-0001-5204-7044
Samantha GreevesDepartment of Chemistry, University of York, York, UK.ORCID https://orcid.org/0000-0003-2936-525X
Kirsty PenkmanDepartment of Chemistry, University of York, York, UK.
Adrian A FinchSchool of Earth and Environmental Sciences, University of St Andrews, St Andrews, UK.
Susan FitzerFaculty of Natural Sciences, Institute of Aquaculture, University of Stirling, Stirling, UK.ORCID https://orcid.org/0000-0003-3556-7624
Roland KrögerSchool of Physics, Engineering and Technology, University of York, York, UK.ORCID https://orcid.org/0000-0002-5070-0297
Alex BrasierSchool of Geosciences, University of Aberdeen, Aberdeen, UK.
John StillSchool of Geosciences, University of Aberdeen, Aberdeen, UK.
Matthieu ClogSUERC, University of Glasgow, Glasgow, UK.
Nicola AllisonSchool of Earth and Environmental Sciences, University of St Andrews, St Andrews, UK.ORCID https://orcid.org/0000-0003-3720-1917

Funding

Natural Environment Research Council NE/S001417/1
6 · The paper itself

Abstract

Biogenic aragonite is a composite of mineral and biomolecules that exhibits superior material properties compared to its inorganic analog. This superiority underpins the success of the bioaragonite structures which support coral reefs and shell fisheries, yet the mechanisms improving the physical resilience of bioaragonite are not well understood. In this study, aragonite is synthesised under chemical conditions which simulate those of calcification sites in marine organisms. Aspartic acid, glutamic acid, and glycine in solution are incorporated into the aragonite at concentrations typically observed in marine biominerals and are observed to significantly improve aragonite Vickers hardness. Aspartic acid is incorporated more efficiently than glutamic acid or glycine, but for comparable amounts of amino acid incorporation, glycine improves aragonite hardness significantly more than either aspartic or glutamic acid. Glycine and glutamic acid incorporation reduce the aragonite grain size, thereby improving resilience to indentation via energy dissipation along grain boundaries. In contrast, aspartic acid also improves hardness on a smaller scale, possibly due to crystal structure distortions. These results suggest that amino acid incorporation influences biogenic aragonite hardness via multiple mechanisms and provide a prototype for exploring the influence of more complicated biomineral proteins.

Indexed as

Calcium CarbonateAmino AcidsAspartic AcidGlutamic AcidGlycineHardnessAmino AcidsAspartic AcidCalcium CarbonateGlutamic AcidGlycineamino acidaragonitehardnessnanograinstructure distortion

Identifiers

PMID42720183
PMCPMC13560609

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.