ArticleChemistry & biodiversity2026
Combining Phytochemical and Computational Approach on Citrus hystrix DC. (Kaffir Lime) Peel Extract: Anti-Diabetic and Anti-Inflammatory Activities.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The peel of Citrus hystrix DC. (kaffir lime), an underexploited agro-industrial by-product, may have bioactives. This work tested the ethanolic extract of C. hystrix peel's (EeChP) phytochemicals by GC-MS profiling, and the antidiabetic effect was evaluated using the alpha-amylase inhibitory test, and the anti-inflammatory activity was done using the human red blood cell (HRBC) membrane model. The antibacterial effect was determined using the agar well diffusion method against Staphylococcus aureus and Escherichia coli. Major constituents subjected to pharmacokinetic and ADMET filtering, molecular docking, Gene Ontology (GO), and KEGG pathway analysis for mechanistic plausibility. The GC-MS detected 44 phytoconstituents, including limonene, γ-sitosterol, and β-amyrin. EeChP inhibited α-amylase (IC
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