Synthesis and Antifungal Evaluation of Isoquinoline-3-amide Derivatives Containing a Phenoxypyridine Moiety for Plant Protection.

Jiayao Zhang, Shuaipeng Sun, Yajing Guo, Zhiyuan Xu, Jing Zhang, Gang Feng, Haixin Ding, Qiang Xiao

Abstract read

In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiayao ZhangJiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang, China.

Shuaipeng SunJiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang, China.

Yajing GuoJiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang, China.

Zhiyuan XuEnvironment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Science, Haikou, China.

Jing ZhangEnvironment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Science, Haikou, China.

Gang FengEnvironment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Science, Haikou, China.ORCID https://orcid.org/0000-0003-0338-6458

Haixin DingJiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang, China.ORCID https://orcid.org/0000-0003-1569-7333

Qiang XiaoJiangxi Provincial Key Laboratory of Organic Functional Molecules, Institute of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang, China.ORCID https://orcid.org/0000-0003-2812-7778

Funding

Chinese Academy of Tropical Agricultural Sciences CATASCXTD202410National Science Foundation of China 32460690Natural Science Foundation of Jiangxi Province 20232BAB205058

6 · The paper itself

Abstract

To discover novel green antifungal candidates, 20 3-acylaminoisoquinoline derivatives were designed and synthesized by introducing the active fragment phenoxypyridine. Their structures were verified by

Indexed as

Antifungal AgentsIsoquinolinesSuccinate DehydrogenaseAscomycotaCrystallography, X-RayPyridinesStructure-Activity RelationshipAntifungal AgentsIsoquinolinesPyridinesSuccinate Dehydrogenaseisoquinoline amidesmolecular dockingphenoxypyridineplant fungicideSDHI

Identifiers

PMID42720078

DOI10.1002/cbdv.71635

PMCPMC13559863

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.