Evidence map›Paper›PMID 42720036›Full record

ArticleFoot & ankle international2026

Motion-Preserving Salvage for Failed Total Ankle Arthroplasty or Talar AVN: Outcomes of Combined Total Ankle Arthroplasty with Custom 3D-Printed Total Talus Replacement.

Rachit Saggar, Richard M Smith, Eva Heidinger, Omar M Yaldo, Carl T Hasselman, MaCalus V Hogan, Alex J Kline

Abstract read
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Article in Foot & ankle international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Rachit SaggarFoot and Ankle Injury Research Group, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-9123-7999
Richard M SmithFoot and Ankle Injury Research Group, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-6330-7726
Eva HeidingerFoot and Ankle Injury Research Group, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0009-0003-9463-8899
Omar M YaldoFoot and Ankle Injury Research Group, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Carl T HasselmanFoot and Ankle Injury Research Group, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
MaCalus V HoganFoot and Ankle Injury Research Group, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-6598-1095
Alex J KlineFoot and Ankle Injury Research Group, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTalar component collapse following total ankle arthroplasty (TAA) and talar avascular necrosis (AVN) with concurrent ankle arthritis represent challenging clinical scenarios. Traditional salvage with tibiotalocalcaneal arthrodesis sacrifices motion and has nonunion rates approaching 30%. This study evaluates outcomes of a motion-preserving salvage strategy: combined TAA with custom 3D-printed total talus replacement (TAA-TTR).

methodsWe retrospectively reviewed consecutive patients who underwent TAA-TTR between September 2020 and December 2023. Indications included talar component collapse following prior TAA or talar AVN with ankle and subtalar arthritis. Subtalar arthrodesis was performed using 2 screws with use of bone marrow aspirate concentrate. Primary endpoint was complication rate; secondary endpoints included reoperations, radiographic assessments, and functional recovery milestones.

resultsEighteen patients (10 females, 8 males; mean age 57.8 ± 10.8 years) were analyzed at mean follow-up of 36.8 ± 16.6 months, after excluding 2 with <12 months' follow-up. Nine had talar AVN and 9 had failed TAA. The complication rate was 33.3% (95% CI: 15.2%-57.3%) (AVN group 44%, revision TAA group 22%). Six patients experienced complications: superficial surgical site infection (SSI) (1), deep SSI requiring debridement surgery (2), extensor hallucis longus rupture (1), nerve-related complication (1), and asymptomatic Chopart joint subluxation (1). Two patients required serial operations, including 1 below-knee amputation for persistent pain and infection. Reoperation rate was 11.1% (95% CI: 3.1%-32.8%). Patients achieved rapid functional recovery: controlled ankle motion boot transition at mean 19.9 days, full weight-bearing at mean 46.9 days, and regular footwear at mean 10.7 weeks. All patients achieved radiographic osseointegration of talar component to the calcaneus.

conclusionTAA-TTR represents a viable motion-preserving procedure in this challenging population. Although patients achieved relatively rapid functional recovery and transition to regular footwear, rigorous selection remains key. This approach demonstrates a manageable complication rate while addressing tibiotalar and subtalar pathology simultaneously. LEVEL OF EVIDENCE: Level IV, retrospective case series.

Indexed as

Ankle JointArthroplasty, Replacement, AnkleOsteonecrosisPrinting, Three-DimensionalSalvage TherapyTalusAgedArthrodesisFemaleHumansJoint ProsthesisMaleMiddle AgedReoperationRetrospective Studies3D-printed implantsubtalar arthrodesistalar avascular necrosistalar component collapsetotal ankle arthroplastytotal talus replacement

Identifiers

PMID42720036
PMCPMC13669449

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.