ArticleBiophotonics discovery2026
Extracorporeal near-infrared-activated antimicrobial photodynamic therapy for pneumonia using an ICG-polymer formulation.
Article in Biophotonics discovery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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Abstract
Significance: Pneumonia remains a global health challenge, exacerbated by antimicrobial resistance, which limits the effectiveness of conventional treatments. Antimicrobial photodynamic therapy (aPDT) has emerged as a promising alternative for lower respiratory infections; however, its Aim: To address this limitation, recent studies demonstrated that combining indocyanine green (ICG) with the polymer Gantrez AN-139 enhances photodynamic activity even in the presence of lung surfactants. Approach: We assessed the therapeutic potential of this formulation in a murine pneumonia model using pulmonary delivery followed by 808 nm infrared irradiation. Results: Nebulization of Conclusion: These findings validate the formulation and the procedure for further animal studies.
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