ReviewDrug design, development and therapy2026
Monkeypox Virus Countermeasures: Vaccines, Antibodies, Drugs and Traditional Chinese Medicine.
Review in Drug design, development and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Monkeypox virus (MPXV) has garnered global attention in recent years. MPXV is a DNA virus that is categorized as belonging to the Orthopoxvirus, exhibiting close genetic and structural similarities to variola virus (VARV) and vaccinia virus (VACV). Despite the World Health Organization (WHO) announcing in 2023 that the global outbreak of monkeypox (mpox) is no longer a public health emergency, the new occurrence reported in most regions shows the urgency of the development of medicines for mpox. In this review, we reviewed a huge amount of literature on mpox, summarizing its development, scientific findings, and trustworthy data when it comes to viral structure, binding targets, treatments, and intervention strategies. Because no antiviral agents have been formally authorized by the US Food and Drug Administration (FDA) or the WHO for the targeted treatment of mpox, coupled with the limited effectiveness demonstrated by current antiviral medications in clinical evaluations, the progressive emergence of drug resistance, and the ongoing threat posed by novel viral variants, the advancement of new antiviral therapeutics for mpox has emerged as an urgent priority within the domain of global public health. The purpose is to explore measures, therapy techniques, and the medication development process for mpox, including vaccines, antibodies, chemicals, natural drug monomers, traditional Chinese medicines (TCM), and Chinese herbal formulations. Also, it clearly differentiates the progress of approved drugs, preclinical candidate compounds, and computer-predicted molecules in the development of therapeutics for mpox. It is beneficial to comprehend MPXV's research basis, improve the understanding of preventive measures and treatment methods, and promote medical and healthcare services.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.