ArticleAnnals of thoracic surgery short reports2026
Feasibility Study of Renal Negative Pressure Treatment After Cardiac Surgery With Cardiopulmonary Bypass.
Article in Annals of thoracic surgery short reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bypass Surgery Incorporating a Negative Pressure Renal Assist Device to Resolve AKI
Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes
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0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: We conducted a technical feasibility and safety study of intraureteric renal negative pressure treatment (rNPT) in patients with chronic kidney disease undergoing elective cardiac surgery with cardiopulmonary bypass. Methods: After written informed consent, 10 patients with preoperative estimated glomerular filtration rate of 15 to 59 mL/min per 1.73 m Results: Three patients had major protocol deviations with primary catheter misplacement; acute kidney injury developed in 1 of these. Bilateral renal pelvis catheters were deployed per protocol in 7 patients. All patients had microhematuria; 2 had transient hematuria. In the per-protocol group, acute kidney injury developed in 1 patient with stage 4 chronic kidney disease. No patient suffered any other major adverse event. Serum creatinine concentration remained normal in 6 patients at 72 hours; and in 5 patients, estimated glomerular filtration rate had improved from baseline at 28 days. Conclusions: rNPT is feasible after cardiac surgery. If catheter placement protocol is strictly followed, it is associated with minimal patient risk and potential benefit. A controlled study (NCT07017933) is in progress to evaluate rNPT started before cardiopulmonary bypass and continued postoperatively. ClinicalTrialsgov identifier: NCT05990660.
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Registered trials
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