ArticlemicroPublication biology2026
A histone H2A docking domain mutant interferes with proper yFACT-gene interactions in
Article in microPublication biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Alterations within the nucleosomal Influences Spt16-Gene Interactions (ISGI) region, which is located on the side of the nucleosome and is comprised of histone H3 and H4 residues, shift yFACT occupancy toward the 3' ends of genes, likely due to defective yFACT dissociation following transcription. Here, we show that a single amino acid substitution within the histone H2A docking domain, H2A-I103A, similarly alters yFACT-gene interactions. These results demonstrate that histone H2A integrity is required for proper yFACT-gene interactions
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.